Abscisic acid enhances aggregation and fusion of phospholipid vesicles |
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Authors: | W Stillwell B Brengle S R Wassall |
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Affiliation: | Department of Biology, Indiana University-Purdue University, Indianapolis. |
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Abstract: | The plant hormone abscisic acid (ABA) is shown to enhance the aggregation and fusion of small unilamellar lipid vesicles composed of 80 mol% dimyristoylphosphatidylcholine (DMPC) and 20 mol% dimyristoylphosphatidylcholine (DMPE). Aggregation and fusion did not occur with single component (100 mol%) DMPC vesicles. Fusion was followed by two fundamentally different techniques, fluorescence resonance energy transfer which monitors intermixing of bilayers and ANTS-DPX which monitors intermixing of the sequestered aqueous interiors. It is suggested that a previously unreported role of ABA may be as a membrane fusagen. |
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