Regional mapping of the gene for human lysosomal acid phosphatase (ACP2) using a hybrid clone panel containing segments of human chromosome 11 |
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Authors: | Carol Jones Fa-Ten Kao |
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Institution: | (1) Eleanor Roosevelt Institute for Cancer Research, Florence R. Sabin Laboratories for Developmental Medicine, 80262 Colorado, Denver, USA;(2) Department of Biophysics and Genetics, University of Colorado Medical Center, 80262 Denver, Colorado, USA |
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Abstract: | Summary A clone panel containing various segments of human chromosome 11 has been selected and used for regional assignment of the gene for human lysosomal acid phosphatase (ACP2) to the short arm of chromosome 11, in the region 11p11 11p12. Further evidence has also been presented to update the regional assignment of the gene for lactate dehydrogenase A (LDHA) to 11p12 11p13, and to support a previous assignment of the genes for the two components of the human cell-surface antigens of the SA11 (previously designated AL) group, SA11-1 and SA11-3 (previously designated AL-a1 and AL-a3), to 11pter 11p13. This regional clone panel will be useful for rapid regional mapping of other genes assigned to chromosome 11. |
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