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Manufacturing Devices and Instruments for Easier Rat Liver Transplantation
Authors:Graziano Oldani  Stephanie Lacotte  Lorenzo Orci  Philippe Morel  Gilles Mentha  Christian Toso
Affiliation:1.Transplantation Division, Department of Surgery, University of Geneva Hospitals;2.Department of Surgery, University of Pavia;3.Department of Surgery, University of Geneva;4.Division of Abdominal Surgery, Department of Surgery, University of Geneva Hospitals
Abstract:Orthotopic rat liver transplantation is a popular model, which has been shown in a recent JoVE paper with the use of the "quick-linker" device. This technique allows for easier venous cuff-anatomoses after a reasonable learning curve. The device is composed of two handles, which are carved out from scalpel blades, one approximator, which is obtained by modifying Kocher''s forceps, and cuffs designed from fine-bore polyethylene tubing. The whole process can be performed at a low-cost using common laboratory material. The present report provides a step-by-step protocol for the design of the required pieces and includes stencils.
Keywords:Medicine   Issue 75   Biomedical Engineering   Bioengineering   Mechanical Engineering   Anatomy   Physiology   Surgery   Tissue Engineering   Liver Transplantation   Liver   transplantation   rat   quick-linker   orthotopic   graft   cuff   clinical techniques   animal model
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