Manufacturing Devices and Instruments for Easier Rat Liver Transplantation |
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Authors: | Graziano Oldani Stephanie Lacotte Lorenzo Orci Philippe Morel Gilles Mentha Christian Toso |
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Affiliation: | 1.Transplantation Division, Department of Surgery, University of Geneva Hospitals;2.Department of Surgery, University of Pavia;3.Department of Surgery, University of Geneva;4.Division of Abdominal Surgery, Department of Surgery, University of Geneva Hospitals |
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Abstract: | Orthotopic rat liver transplantation is a popular model, which has been shown in a recent JoVE paper with the use of the "quick-linker" device. This technique allows for easier venous cuff-anatomoses after a reasonable learning curve. The device is composed of two handles, which are carved out from scalpel blades, one approximator, which is obtained by modifying Kocher''s forceps, and cuffs designed from fine-bore polyethylene tubing. The whole process can be performed at a low-cost using common laboratory material. The present report provides a step-by-step protocol for the design of the required pieces and includes stencils. |
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Keywords: | Medicine Issue 75 Biomedical Engineering Bioengineering Mechanical Engineering Anatomy Physiology Surgery Tissue Engineering Liver Transplantation Liver transplantation rat quick-linker orthotopic graft cuff clinical techniques animal model |
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