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Simulation of cellular compaction and internalization in mammalian embryo development as driven by minimization of surface energy |
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| Authors: | Narendra S. Goel Carlos F. Doggenweiler Richard L. Thompson |
| Affiliation: | (1) Department of Systems Science, State University of New York, Binghamton, 13901 New York, NY, USA;(2) Present address: Department of Biology, University of Chile, Casilla 653, Santiago, Chile;(3) Cavendish Laboratory, Madingley Road, CB3 0HE Cambridge, England;(4) Present address: La Jolla Institute, P.O. Box 1434, 92038 La Jolla, CA, USA |
| Abstract: | A model based upon minimization of surface energy is proposed as an explanation for compaction and internalization of cells during mammalian embryo development. The model is used to simulate and graphically display these phenomena on a computer. |
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