Phosphorylation at the interface |
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Authors: | Davis Fred P |
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Institution: | Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Dr., Ashburn, VA 20147, USA. davisf@janelia.hhmi.org |
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Abstract: | Proteomic studies have identified thousands of eukaryotic phosphorylation sites (phosphosites), but few are functionally characterized. Nishi et?al., in this issue of Structure, characterize phosphosites at protein-protein interfaces and estimate the effect of their phosphorylation on interaction affinity, by combining proteomics data with protein structures. |
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