An ovarian independent population of uterine estrogen receptors |
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| Authors: | Valerie E Quarmby Kenneth S Korach |
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| Institution: | Laboratory of Reproductive and Developmental Toxicology National Institute of Environmental Health Sciences Research Triangle Park, North Carolina 27709, USA |
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| Abstract: | Estrogen receptor levels in uteri from ovariectomized mice varied markedly with time after surgery; these changes were not due to nuclear translocation. Receptor cyclicity was abolished in ovariectomized-adrenalectomized mice, and receptor levels remained low. This indicates that the adrenals significantly influenced uterine estrogen receptor levels. However, these adrenal-mediated changes did not alter uterine responsiveness to estrogen stimulation. |
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