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A model for the firing pattern of a paced nerve cell
Authors:Morten Colding-Jørgensen
Affiliation:Institute of Medical Physiology, Dept. A, The Panum Institute, Blegdamsvej 3C DK-2200, Copenhagen N, Denmark
Abstract:When a nerve cell is paced by another cell or by external stimuli, its firing pattern is generally not regular. In a given stimulus and frequency interval the cell responds only on a fraction of the stimuli, and this fraction is not necessarily a nice simple fraction as 2, ;, etc. but may be any fraction less than one, why the firing pattern becomes accordingly irregular.The paper demonstrates the rules for these irregularities and supplies a mathematical tool to analyse the firing pattern. In the analysis only a cell with the so-called impulse dependent type of adaptation is considered, but similar analyses may be done with other cell types.The analysis is restricted to a case where a resting cell is stimulated by repetitively applied stimuli of constant strength and repetition frequency. Cases with more than one input, spontaneously firing cells, and transient phenomena are not included in the analysis.
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