Studies of a possible relationship of brain proteins to changes in behavioral sensitivity to DFP

Whether behavioral differences in selectively bred lines of rats could be attributed to changes in the enzymes acetylcholinesterase and glutathione S-transferase in different brain regions have been examined. Electrophoresis of the brain proteins has been studied and compared to one another and to that of control animals. The results presented suggest that differences in behavior are associated with changes in the level of brain enzymes, although not with changes in the properties of the enzymes $\text{per}$$\text{se}$.