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Functional role of plateau potentials in vertebrate motor neurons |
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| Authors: | Ole Kiehn Torsten Eken |
| Affiliation: | aSection of Neurophysiology, Department of Medical Physiology, Panum, Blegdamsvej 3, 2200 Copenhagen N, Denmark;bDepartment of Anaesthesiology, Aker Hospital, University of Oslo, N-0514 Oslo, Norway |
| Abstract: | The expression of plateau potentials in spinal motor neurons is regulated by neuromodulatory substances. Recent experiments have shed new light on this regulation at the cellular level. It is now possible to evaluate the existence of plateau potentials in intact organisms, including humans, and to address the functional role of plateau potentials in motor control, as well as in information transfer in the brain. |
| Keywords: | Abbreviations: 5-HT 5-hydroxytryptamine GABA γ-aminobutyric acid EMG electromyography EPSP excitatory postsynaptic potential ICAN calcium-activated nonselective cationic current Ih hyperpolarization-activated inward current I—V current—voltage mGlu metabotropic glutamate (receptor) NMDAN-methyl- font-variant: small-caps" >d-aspartic acid NSR negative slope conductance region |
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