| Abstract: | In vivo phagocytosis by peripheral blood leucocytes of the dogfish Scyliorhinus canicula L. was examined by monitoring the fate of a variety of injected materials, both particulate and soluble, in normal and immunised fish. Carbon, yeasts and bacteria were phagocytosed by monocytes, thrombocytes and type 1 granulocytes (neutrophils). Quantitative in vivo antigen clearance studies employed five species of bacteria, yeast and KLH. After an initial significant decrease of these antigens in the circulation, low numbers of viable bacteria and yeasts and low concentrations of KLH persisted for long periods after injection. Previous exposure to several of these antigens had little or no effect. |
