The Drosophila wing test: a comparison of the sensitivity of different strains |
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| Authors: | J Clements D Howe M Phillips N K Todd |
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| Institution: | Department of Biology, University of York, Heslington, Great Britain. |
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| Abstract: | A range of 5 chemical mutagens were tested in the Drosophila wing test using 2 different strains and carrying out the experiments in parallel under standardised conditions. The mutagens chosen for the study were the 2 alkylating agents MMS and ENU and the anti-cancer drugs methotrexate, cytosine-arabinoside and adriamycin. As a result of the different genetic backgrounds there was a marked variation in the response of the 2 strains to the mutagens. |
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