STDP rule endowed with the BCM sliding threshold accounts for hippocampal heterosynaptic plasticity |
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Authors: | Lubica Benuskova Wickliffe C Abraham |
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Institution: | (1) Knowledge Engineering & Discovery Research Institute, Auckland University of Technology, Auckland, New Zealand;(2) Department of Applied Informatics, Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava, Slovakia;(3) Department of Psychology, University of Otago, Dunedin, New Zealand |
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Abstract: | We have combined the nearest neighbour additive spike-timing-dependent plasticity (STDP) rule with the Bienenstock, Cooper
and Munro (BCM) sliding modification threshold in a computational model of heterosynaptic plasticity in the hippocampal dentate
gyrus. As a result we can reproduce (1) homosynaptic long-term potentiation of the tetanized input, and (2) heterosynaptic
long-term depression of the untetanized input, as observed in real experiments.
Action Editor: Nicolas Brunel |
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Keywords: | Heterosynaptic plasticity Metaplasticity STDP Sliding BCM threshold |
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