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The involvement of the electron transport chain in uptake of testosterone by membrane vesicles of Pseudomonas testosteroni
Affiliation:1. School of Environmental Science and Engineering, Academy of Environment and Ecology, Tianjin University, No. 92 Weijin Road, Nankai District, Tianjin 300072, China;2. State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, No. 73 Huanghe Road, Nangang District, Harbin 150090, China;1. Division of Regenerative Medicine and Cellular Therapies, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom;2. Walgreens Boots Alliance, Nottingham NG2 3AA, United Kingdom;3. Division of Advanced Materials and Health Technologies, School of Pharmacy, University of Nottingham, NG7 2RD, United Kingdom;4. Division of Biomolecular Science and Medicinal Chemistry, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom;5. Division of Molecular Therapeutics and Formulation, School of Pharmacy, University of Nottingham, Nottingham NG7 2RD, United Kingdom;6. SLIM Imaging Unit, Faculty of Medicine and Health Sciences, School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom
Abstract:Uptake of testosterone by membrane vesicles of Pseudomonas testosteroni is inhibited when examined under anaerobic conditions and in the presence of the electron transport chain inhibitors, sodium amytal and antimycin A. These results indicated the involvement of the electron transport chain in steroid uptake by membrane vesicles.
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