Sex steroid induced morphological changes in primary uterine cell cultures |
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| Affiliation: | 2. St Vincent''s Hospital Melbourne, Interventional Radiology Department, 41 Victoria Parade, Fitzroy VIC 3065, Australia;1. Department of Radio-Diagnosis, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu, 602105, India;2. Department of Radio-Diagnosis, Apollo Hospitals, Jubilee Hills, Hyderabad, Telangana, 500033, India;1. Department of Diagnostic Radiology, NHO Shikoku Cancer Center, Matsuyama, Japan;2. Department of Gastroenterological Surgery, NHO Shikoku Cancer Center, Matsuyama, Japan;3. Department of Pathology, NHO Shikoku Cancer Center, Matsuyama, Japan |
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| Abstract: | The ultrastructure of primary cultures of endometrial cells after treatment with diethystilbestrol, progesterone, and hydrocortisone was examined using the method of electronmicroscopic stereology. Cells treated with diethylstilbestrol had the appearance of a rapidly dividing culture having large euchromatic nuclei and prominent nucleoli with a cytoplasm containing many free ribosomes. Progesterone appeared to convert the cells to a more secretory type with large amounts of RER and smaller nucleoli. Mitochondrial enlargement was induced by sex hormones but not by hydrocortisone. |
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