FSH,LH, TeBG-capacity,estrogen and progesterone in women with premenstrual tension during the luteal phase |
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Affiliation: | 1. Department of Clinical Medicine and Translational Psychiatry Research Group, Faculty of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil;2. Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, Australia;3. Department of Psychiatry, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand;4. Department of Psychiatry, Faculty of Medicine, State University of Londrina, Londrina, Brazil;5. Department of Psychiatry, Medical University Plovdiv, Plovdiv, Bulgaria;6. Revitalis, Waalre, The Netherlands;7. Center for Clinical and Epidemiological Research & Interdisciplinary Center for Applied Neuromodulation (CINA), University Hospital, University of São Paulo, São Paulo, Brazil;8. Service of Interdisciplinary Neuromodulation (SIN), Department and Institute of Psychiatry, Faculty of Medicine of University of São Paulo, São Paulo, Brazil;9. Laboratory of Neuroscience (LIM27), Department and Institute of Psychiatry, University of São Paulo, São Paulo, Brazil;10. Laboratório de Neurociências, Programa de Pós-Graduação em Ciências da Saúde, Unidade Acadêmica de Ciências da Saúde, Universidade do Extremo Sul Catarinense, Criciúma, Brazil;11. Center for Translational Psychiatry, Department of Psychiatry and Behavioral Sciences, The University of Texas Medical School at Houston, Houston, USA;12. Laboratory of Calcium Binding Proteins in the Central Nervous System, Department of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;13. Department of Experimental and Clinic Medicine, Section of Psychiatry, University of Pisa, Pisa, Italy;14. Institute of Behavioral Sciences “G. De Lisio”, Pisa, Italy;15. Department of Psychiatry, Faculty of Medicine, School of Health Sciences, University of Ioannina, Greece;1. Faculty of Medicine, School of Public Health, Centre for Longitudinal and Life Course Research, The University of Queensland, Brisbane, Queensland, Australia;2. Faculty of Health Sciences & Medicine, Bond University, Gold Coast, Queensland, Australia;1. Department of Educational Psychology and Pedagogy, Begoñako Andra Mari Teacher Training University College, BAM, Bilbao, Spain;2. Department of Psychology, University of the Basque Country UPV/EHU, Donostia-San Sebastian, Spain;3. Faculty of Psychology and Educational Sciences, Katholieke Universiteit Leuven, Leuven, Belgium |
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Abstract: | Plasma immunoreactive estrogen was significantly lower on days 9 and 8 before menstruation in a group of 15 women with premenstrual tension (PMT) syndrome, than in a control group of 17 women. Estrogen thereafter started to increase and was significantly higher in the PMT-group than in the controls on day 5 before menstruation. This increase was significant until day 1 before menstruation. Progesterone levels were constantly lower in the PMT-group than in the controls.The mean FSH level in plasma in PMT patients was significantly increased above controls on day 9, 8, 7 and 6 before menstruation. No difference between groups was seen in LH levels nor in serum albumin and binding capacity of testosterone-estradiol binding globulin (TeBG), neither could changes in LH, albumin or TeBG capacity explain the increase seen in estrogen concentration. The possible role of FSH in the PMT syndrome is discussed in order to explain the increased estrogen secretion. |
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