A minireview of microheterogeneity in H1 histone and its possible significance |
| |
Authors: | R D Cole |
| |
Institution: | Department of Biochemistry, University of California, Berkeley, California 94720 USA |
| |
Abstract: | Subtypes of H1 histone vary in primary structure, and the higher organisms that have been studied each seem to have about a half-dozen subtypes. The proportions of these subtypes vary with the progress of differentiation as seen in embryonic development, hormonally induced changes, spermatogenesis, and terminal differentiation. The H1 subtypes differ among themselves in their ability to condense DNA and small chromatin fragments. They have the potential, therefore, of causing different parts of the chromatin to be condensed to different degrees. |
| |
Keywords: | microheterogeneity H1 histone chromatin structure chromatin condensation circular dichroism—nucleohistones |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|