Insect feeding deterrent activity of bisabolangelone and of some sesquiterpenes of eremophilane type

The insect feeding deterrent activity of some sesquiterpenes of furanoeremophilane type and of the related eremophilanolide type were tested towards three selected storage pests: Sitophilus granarius, Tribolium confusum and Trogoderma granarium. The results were compared with the biogenetically related compound of bakkenolide type, known as a potent antifeedant. Bisabolangelone, tested on the same insects, exhibited the strongest activity, and may be included in the class of very good insect feeding deterrents. The antifeeding activity of bisabolangelone and bakkenolide A towards larvae of Leptinotarsa decemlineata was also observed.