Involvement of human membrane-associated complement components in the rosette formation between marmoset red blood cells and human leukocytes |
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| Authors: | J L Teillaud C Goujet-Zalc M Fontaine C Braun G Mahouy |
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| Institution: | 1. Institut de Recherches sur les Maladies du Sang, Laboratoire des Interactions lymphocytaires, Hôpital Saint-Louis, 75475 Paris Cedex 10, France;2. INSERM U78, 543 Chemin de la Bretèque, 76230 Bois-Guillaume, France |
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| Abstract: | The majority of human monocytes, a subpopulation of B lymphocytes, and all B lymphoblastoid cell lines (B-LCL) tested but one form rosettes with Marmoset red blood cells (MaRBC). None of the human peripheral T cells, T-LCL, and B chronic lymphoid leukemia cells (B-CLL) used bind to MaRBC. The binding could not be correlated with any membrane markers or antigens present on cultured cells or peripheral blood leukocytes (PBL). Blocking of the rosette formation by preincubation of MaRBC with purified human complement (C) components and cobra venom or by pretreatment of leukocytes and cultured cells with antisera to human C components suggested that membrane-associated C components present on PBL or B-LCL are involved in the binding to MaRBC. |
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| Keywords: | To whom correspondence should be sent |
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