Synthesis of fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines |
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| Authors: | Wu Yong-Jin He Huan Sun Li-Qiang Wu Dedong Gao Qi Li Hui-Yin |
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| Institution: | Department of Neuroscience Chemistry, The Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492, USA. young-jin.wu@bms.com |
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| Abstract: | The synthesis of four (+/-)-fluorinated 1-(3-morpholin-4-yl-phenyl)-ethylamines and an enantioselective approach to these amines through reductive amination are described. |
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