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Y-chromosome haplotype distribution in Han Chinese populations and modern human origin in East Asians |
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| Authors: | Yuehai Ke Bing Su Junhua Xiao Hua Chen Wei Huang Zhu Chen Jiayou Chu Jiazhen Tan Li Jin Daru Lu |
| Affiliation: | (1) Institute of Genetics and Morgan-Tan International Center for Life Science, Fudan University, 200433 Shanghai, China;(2) Kunming Institute of Zoology, Chinese Academy of Sciences, 650223 Kunming, China;(3) Human Genetics Center, University of Texas-Houston, 77225 Houston, USA;(4) National Human Genome Center at Shanghai, 201203 Shanghai, China;(5) Institute of Medical Biology, Chinese Academy of Medical Sciences, 650031 Kunming, China |
| Abstract: | We investigated the distribution of Y-chromosome haplotype using 19 Y-SNPs in Han Chinese populations from 22 provinces of China. Our data indicate distinctive patterns of Y chromosome between southern and northern Han Chinese populations. The southern populations are much more polymorphic than northern populations. The latter has only a subset of the southern haplotypes. This result confirms the genetic difference observed between southern and northern ethnic populations in East Asia. It supports the hypothesis that the first settlement of modern humans of African origin occurred in the southern part of East Asia during the last Ice Age, and a northward migration led to the peopling of northern China. |
| Keywords: | Y-chromosome haplotype SNPs modern human origin emigration Chinese. |
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