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MAP3K2 augments Th1 cell differentiation via IL-18 to promote T cell-mediated colitis |
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| Authors: | Wu Ningbo Chen Dongping Sun Hongxiang Tan Jianmei Zhang Yao Zhang Tianyu Han Yuheng Liu Hongzhi Ouyang Xinxing Yang Xiao-Dong Niu Xiaoyin Zhong Jie Wang Zhengting Su Bing |
| Institution: | 1.Shanghai Institute of Immunology, Department of Immunology and Microbiology, and Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, China ;2.Shanghai JiaoTong University School of Medicine-Yale Institute for Immune Metabolism, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, China ;3.Department of Gastroenterology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, 200025, China ; |
| Abstract: | Science China Life Sciences - T cell-mediated immunity in the intestine is stringently controlled to ensure proper immunity against pathogenic microbes and to prevent autoimmunity, a known cause of... |
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