An extended genetic linkage map of markers for human chromosome 10 |
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Authors: | Yusuke Nakamura Mark Lathrop Tara Bragg Mark Leppert Peter O'Connell Carol Jones Jean-Marc Lalouel Ray White |
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Institution: | Howard Hughes Medical Institute, University of Utah Health Sciences Center, Salt Lake City 84132. |
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Abstract: | We have extended, in both directions, our recently published genetic map of markers for human chromosome 10 by the addition of 10 newly defined arbitrary loci. The map now covers 230 cM in males and 329 cM in females. In addition, three new markers, one of them a new RFLP at the IRBP gene locus, have been mapped in the vicinity of the locus responsible for multiple endocrine neoplasia type 2A (MEN2A). A significantly higher frequency of recombination in males than in females was observed near both ends of the new map. |
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