Δ-β-Sitosten-3-one from β-sitosterol by leaf homogenates |
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Authors: | S J Stohs and M M El-Olemy |
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Institution: | College of Pharmacy, University of Nebraska, Lincoln, Nebraska 68508, U.S.A. |
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Abstract: | β-Sitosterol-4-14C is metabolized to Δ4-β-sitosten-3-one by Cheiranthus cheiri leaf homogenates. Greater than 60% conversion occurs within 2 hr. Under identical conditions, leaf homogenates of Strophanthus kombé fail to metabolize β-sitosterol, while Digitalis purpurea leaf homogenates yield only very small amounts of the metabolite. |
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