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Synthesis of pyochelin-norfloxacin conjugates
Authors:Rivault Freddy  Liébert Clémence  Burger Alain  Hoegy Françoise  Abdallah Mohamed A  Schalk Isabelle J  Mislin Gaëtan L A
Institution:Métaux et Microorganismes: Chimie, Biologie et Applications, UMR 7175-LC1 Institut Gilbert Laustriat CNRS-Université Louis Pasteur (Strasbourg I), ESBS, Boulevard Sébastien Brant, F-67400 Illkirch, France.
Abstract:Using synthetic functionalized analogues of pyochelin, a siderophore common to several pathogenic Pseudomonas and Burkholderia species, four fluoroquinolone-pyochelin conjugates were efficiently synthesized and evaluated for their biological activities.
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