Synthesis of pyochelin-norfloxacin conjugates |
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Authors: | Rivault Freddy Liébert Clémence Burger Alain Hoegy Françoise Abdallah Mohamed A Schalk Isabelle J Mislin Gaëtan L A |
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Institution: | Métaux et Microorganismes: Chimie, Biologie et Applications, UMR 7175-LC1 Institut Gilbert Laustriat CNRS-Université Louis Pasteur (Strasbourg I), ESBS, Boulevard Sébastien Brant, F-67400 Illkirch, France. |
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Abstract: | Using synthetic functionalized analogues of pyochelin, a siderophore common to several pathogenic Pseudomonas and Burkholderia species, four fluoroquinolone-pyochelin conjugates were efficiently synthesized and evaluated for their biological activities. |
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