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Antimicrobial activity and chemical investigation of Brazilian Drosera
Authors:Ferreira Dalva Trevisan  Andrei César Cornélio  Saridakis Halha Ostrensky  Faria Terezinha de Jesus  Vinhato Elisângela  Carvalho Kátia Eliane  Daniel Juliana Feijó Souza  Machado Sílvio Luiz  Saridakis Dennis Panayotis  Braz-Filho Raimundo
Affiliation:Departamento de Química, Centro de Ciências Exatas, Universidade Estadual de Londrina, Caixa Postal 6001, 86051-970 Londrina, PR, Brazil. dalva@uel.br
Abstract:The antimicrobial activity of three different extracts (hexanic, ethyl acetate, methanol) obtained from Brazilian Drosera species (D. communis, D. montana var. montana, D. brevifolia, D. villosa var. graomogolensis, D. villosa var. villosa, Drosera sp. 1, and Drosera sp. 2 ) were tested against Staphylococcus aureus (ATCC 25923), Enterococcus faecium (ATCC23212), Pseudomonas aeruginosa (ATCC27853), Escherichia coli (ATCC11229), Salmonella choleraesuis (ATCC10708), Klebsiella pneumoniae (ATCC13883), and Candida albicans (a human isolate). Better antimicrobial activity was observed with D. communis and D. montana var. montana ethyl acetate extracts. Phytochemical analyses from D. communis, D. montana var. montana and D. brevifolia yielded 5-hydroxy-2-methyl-1,4-naphthoquinone (plumbagin); long chain aliphatic hydrocarbons were isolated from D. communis and from D. villosa var. villosa, a mixture of long chain aliphatic alcohols and carboxylic acids, was isolated from D. communis and 3b-O-acetylaleuritolic acid from D. villosa var. villosa.
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