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Molecular detection of a translocation (Y;15) in a 45,X male
Authors:C. M. Disteche  L. Brown  H. Saal  C. Friedman  H. C. Thuline  D. I. Hoar  R. A. Pagon  D. C. Page
Affiliation:(1) Department of Pathology SM-30, University of Washington, 98195 Seattle, WA, USA;(2) Whitehead Institute, Nine Cambridge Center, 02142 Cambridge, MA, USA;(3) Department of Pediatrics and Medicine, University of Washington, 98195 Seattle, WA, USA;(4) Genetics Services Section, State of Washington, Department of Social and Health Services, 98155 Seattle, WA, USA;(5) Molecular Diagnosis Laboratory, Division of Medical Genetics, Alberta Children's Hospital Research Center, T21 5C7 Calgary, Alberta, Canada
Abstract:Summary A 45,X male individual was shown to have a translocation of Y-chromosome material to the short arm or proximal long arm of chromosome 15. This translocation was detected by genomic DNA blotting and in situ hybridization with Y-chromosome-specific DNA probes.
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