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Mapping of the two mitochondrial antimycin A resistance loci in Saccharomyces cerevisiae.
Authors:Georg Michaelis and Elke Pratje
Institution:(1) Fakultät für Biologie der Universität Bielefeld, Postfach 8640, D-4800 Bielefeld 1, Federal Republic of Germany
Abstract:Summary Retention or loss of the two new mitochondrial antimycin A resistance loci AI and AII has been analyzed in a large number of stable cytoplasmic petite mutants. Using these deletion mutants it was possible to localize the two antimycin A resistance loci in the OI-OII region of mitochondrial DNA. The genetic loci are mapped in the following order: OII-AI-AII-cobl-OI. The mapping relationship of mutants resistant to antimycin A or funiculosin to various cob mutants is described.
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