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Polyamines in inflammation and their modulation by conventional anti-inflammatory drugs
Authors:Chakradhar Lagishetty V  Naik Suresh Ramnath
Institution:Department of Pharmacology and Toxicology, Prin. K.M.Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Mumbai 400 005, India.
Abstract:Significant increase in polyamines levels in inflamed tissue was observed in the experimental animal models of inflammation. Treatment with dexamethasone positively modulated the levels of polyamines whereas non-steroidal drugs, diclofenac and valdecoxib negatively modulated their levels.
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