Changes in acetoacetate/beta-hydroxybutyrate ratio in arterial blood following hepatic artery embolization in man |
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Authors: | T Tani Y Taki H Aoyama A Jikkoh S Arii K Ozawa T Tobe |
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Affiliation: | Department of Surgery, Kyoto University Medical School, Sakyo-ku, Kyoto 606, Japan |
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Abstract: | Acetoacetate/beta-hydroxybutyrate ratio in the hepatic venous blood was compared to the ratios in arterial blood and peripheral venous blood in hypoxic state following right hepatic artery embolization in 5 patients with liver cancer. Ketone body ratios in right hepatic venous blood were positively correlated with those in arterial blood (r = 0.960, p less than 0.001), but not with those in peripheral venous blood. The free NAD+/NADH ratio of the liver mitochondria, which is reflected by the ketone body ration in hepatic venous blood, can be evaluated by the ketone body ratio in the arterial blood. |
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