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Vasoactive intestinal polypeptide (VIP): current status
Authors:S I Said
Institution:1. University of Oklahoma Health Sciences Center Oklahoma City, OK 73190 USA;2. Veterans Administration Medical Center Oklahoma City, OK 73190 USA
Abstract:Research on VIP continues at a rapid pace. Recent progress includes: insights into its biosynthesis (and that of a closely related PHI-like peptide) and its neuronal localization, discovery of novel biological actions, new data on its release and binding to specific receptors, and additional evidence for its roles in physiological regulation and in the pathogenesis of disease.
Keywords:Neurotransmitter  Neuropeptide  Smooth muscle  Vasodilation  Nonadrenergic noncholinergic relaxation  Exocrine function  Reproductive function  Gastrointestinal disease
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