Rat liver microsomal palmitoyl-coenzyme A synthetase. Structural properties |
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| Authors: | J. Bar-Tana and G. Rose |
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| Affiliation: | Department of Biochemistry, The Hebrew University–Hadassah Medical School, Jerusalem, Israel |
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| Abstract: | The structural properties of purified palmitoyl-CoA synthetase from rat liver microsomal material were investigated. The active enzyme has a molecular weight of 168000 and contains about 8.2mol of phospholipid bound/mol of enzyme protein, as well as bound fatty acids. Association of the active enzyme was shown to occur, without impairment of catalytic activity. The lowest-molecular-weight species obtained under denaturing conditions was 27000 daltons. |
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