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JANE: efficient mapping of prokaryotic ESTs and variable length sequence reads on related template genomes |
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| Authors: | Chunguang Liang Alexander Schmid María José López-Sánchez Andres Moya Roy Gross J?rg Bernhardt Thomas Dandekar |
| Affiliation: | (1) Department of Bioinformatics, Biocenter, University of W?rzburg, Am Hubland, D-97074, W?rzburg, Germany;(2) Department of Evolutionary Genetics, Institut Cavanilles de Biodiversitat i Biologia Evolutiva, University of Valencia, Valencia, Spain;(3) Department of Microbiology, Biocenter, University of W?rzburg, Am Hubland, D-97074, W?rzburg, Germany;(4) Institute for Microbiology, Ernst-Moritz-Arndt-University Greifswald, Jahnstrasse 15, 17487 Greifswald, Germany;(5) EMBL, Postbox 102209, D-69012 Heidelberg, Germany |
| Abstract: | BackgroundESTs or variable sequence reads can be available in prokaryotic studies well before a complete genome is known. Use cases include (i) transcriptome studies or (ii) single cell sequencing of bacteria. Without suitable software their further analysis and mapping would have to await finalization of the corresponding genome. |
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