Antioxidant and xanthine oxidase inhibitory activities of total polyphenols from onion |
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| Authors: | Hui Ouyang Kun Hou Wanxi Peng Zhenling Liu Heping Deng |
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| Institution: | 1. Hunan Engineering Laboratory for Analyse and Drugs Development of Ethnomedicine in Wuling Mountains, and Key Laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Jishou 416000, China;2. School of Materials Science and Engineering, Central South University of Forestry and Technology, Changsha 410004, China;3. School of Management, Henan University of Technology, Zhengzhou 450001, China |
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| Abstract: | Onions (Allium cepa L.) comprise a valuable vegetable crop in many countries. Modern scientific research has shown that onions possess many biological activities, including antibacterial, anticancer, hypoglycemic, hypolipidemic, antiplatelet aggregation, and antioxidant activities. The goal of this study was to investigate the impact of total onion polyphenols on antioxidant and xanthine oxidase (XO) inhibitory activities. Total onion polyphenols showed significant antioxidant activity in DPPH, FRAP, and OH-assays (IC50 µg/mL]), 43.24, 560.61, and 12.97, respectively). In a X/XO system, antioxidant properties of these polyphenols significantly inhibited XO activity (IC50 µg/mL], 17.36). These results indicated that total onion polyphenols showed promising antioxidant and anti-gout properties and might be used as potential, natural drugs against oxidative diseases after successful studies in vivo as well as clinical trials. |
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| Keywords: | Total polyphenols Onion Antioxidant Xanthine oxidase Inhibitory activities |
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