Accuracy of phylogeny reconstruction methods combining overlapping gene data sets |
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Authors: | Anne Kupczok Heiko A Schmidt Arndt von Haeseler |
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Affiliation: | 1.Center for Integrative Bioinformatics Vienna, Max F. Perutz Laboratories, University of Vienna, Medical University of Vienna, University of Veterinary Medicine Vienna,Vienna,Austria;2.IST Austria,Klosterneuburg,Austria |
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Abstract: | Background The availability of many gene alignments with overlapping taxon sets raises the question of which strategy is the best to infer species phylogenies from multiple gene information. Methods and programs abound that use the gene alignment in different ways to reconstruct the species tree. In particular, different methods combine the original data at different points along the way from the underlying sequences to the final tree. Accordingly, they are classified into superalignment, supertree and medium-level approaches. Here, we present a simulation study to compare different methods from each of these three approaches. |
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