INAA of serum zinc of inhabitants in five regions of the Czech Republic |
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Authors: | Kvicala Jan Jiránek Václav |
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Institution: | (1) Institute of Endocrinology, Národní 8, 116 94, Prague 1, Czech Republic;(2) Immunotech, a.s., Radiová 1, 102 27, Prague 10, Czech Republic |
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Abstract: | To investigate the Zn status of inhabitants of the Czech Republic, 1155 serum and 132 hair samples were analyzed for zinc
content. Analyzed material was obtained from randomly selected volunteers of both sexes in the age range 6–65 yr. Subpopulations
from five regions were included in the study. Analyses of both materials were performed by Instrumental Neutron Activation
Analysis (INAA). Coanalyses of Standard Reference Materials (SRM) for quality control were performed. The results (mean 910
±276 Μg Zn/L serum and 189 ±45 Μg Zn/g hair) demonstrate satisfactory zinc status of the searched population. Significant
interregional differences and age-dependent differences, as well as sex-dependent differences have been detected by the use
of correlation analysis. On the basis of these results, serum Zn concentration results of individual categories according
to age and sex were evaluated, and on the grounds of mean ±2 standard deviations, indicative intervals were calculated. The
frequency of individual serum Zn concentrations proved that the population of the Czech Republic does not suffer from severe
zinc deficiency. On the other hand, about one-third of our inhabitants has their serum Zn concentrations below the cutoff
value of 800 Μg Zn/L serum, which means a marginal or mild Zn deficit of the organism. |
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Keywords: | Zinc status serum zinc hair zinc zinc deficiency age-dependent differences sex-dependent differences interregional differences indicative intervals |
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