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Okadaic acid: a new probe for the study of cellular regulation |
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| Authors: | P Cohen C F Holmes Y Tsukitani |
| Institution: | Department of Biochemistry, University of Dundee, UK. |
| Abstract: | The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins. |
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