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Activity of cholinergic system enzymes in the cochlea of mice sensitized for audiogenic seizure.
Authors:A Ebel  G Ayad  S Simler  V Stefanovic  R Collins  P Mandel
Affiliation:Centre de Neurochimie du CNRS, and Institut de Chimie Biologique, Faculté de Médecine, 67085 Strasbourg Cedex, France
Abstract:Activity of the enzymes of cholinergic system was investigated in the cochlea of mice sensitized for audiogenic seizure by priming and compared with genetically audiogenic seizure susceptible mice. Higher choline acetyltransferase activity was found in the cochlea of primed mice as well as in the cochlea of audiogenic seizure susceptible mice as previously stated. A possible interpretation of these data is discussed.
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