The effect of high-frequency stimulation of the midbrain reticular formation on the interaction of neocortical neurons]

The influence was studied of midbrain reticular formation (NRT) stimulation at the rate of 75-100 Hz by the current of 33-400 mkA upon the neuronal interaction in the visual and somatosensory regions of rabbits neocortex. Histograms of cross- and autocorrelation of impulse trains were plotted. NRT stimulation resulted (as compared with calm wakefulness) in an increase of the number of pairs of neurons with correlated activity and in an increase of the probability of neurons discharges 100-400 ms one after another. Mechanisms of cellular interaction did not change. Comparison with the previously obtained data allowed to conclude that NRT activation can induce certain changes in neuronal interaction observed during pseudoconditioning and early phases of conditioning.