Immunization of mice against various strains of Pseudomonas aeruginosa by using Pseudomonas lectin vaccine

The ability of Pseudomonas aeruginosa purified lectin vaccine to protect ICR mice against lethal infection caused by various serotypes of this bacterium was examined. Intraperitoneal injection of the lectin preparation was effective in full protection of the mice against the homologous strain. It was also effective in conferring from a partial to a full protection against most of the other virulent strains tested. The only strain which was still lethal for the immunized mice was one which produces exotoxin A but not lectins.