A case series on the potential effect of omega-3-fatty acid supplementation on 24-h heart rate variability and its circadian variation in children with attention deficit (hyperactivity) disorder |
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| Authors: | Reiner Buchhorn Julian Koenig Marc N Jarczok Hanna Eichholz Christian Willaschek Julian F Thayer Michael Kaess |
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| Institution: | 1.Department of Paediatrics, Klinik für Kinder- und Jugendmedizin,Caritas Krankenhaus,Bad Mergentheim,Germany;2.Section for Translational Psychobiology in Child and Adolescents Psychiatry, Department of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine,Heidelberg University,Heidelberg,Germany;3.Institute of Medical Psychology, Center for Psychosocial Medicine,Heidelberg University,Heidelberg,Germany;4.Department of Psychology,The Ohio State University,Columbus,USA;5.Clinic for Child and Adolescent Psychiatry,University Hospital Heidelberg,Heidelberg,Germany |
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| Abstract: | Attention deficit disorder with and without hyperactivity (ADHD) in children is associated with decreased 24-h heart rate variability (HRV). Previous research has shown that supplementation of omega-3-fatty acid increases HRV. Here, we aimed to investigate whether the supplementation of omega-3-fatty acids would increase 24-h HRV in an uncontrolled case series of children with ADHD. HRV was recorded in 18 children and adolescents (age 13.35 ± 2.8 years) before and after omega-3 supplementation. Preliminary results indicate that omega-3 supplementation in children with AD(H)D may reduce mean heart rate and increase its variability. Future studies would do well to implement randomized, placebo-controlled designs with greater methodological rigor. |
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