| 自由活动大鼠睡眠状态和呼吸节律的同步监测方法 |
| |
| 作者姓名： | Wang J Wang GF Ling YL |
| |
| 作者单位： | 1. 河北医科大学病生理教研室,河北,石家庄,050017
2. 北京大学第一医院呼吸科,北京,100034 |
| |
| 摘 要： | 目的:设计一种睡眠呼吸暂停综合征动物模型的监测方法.方法:通过多导生理仪同步监测自由活动大鼠6 h生理睡眠时间的皮层脑电、颈部肌电,以及呼吸波形.并用人机交互的方法进行数据处理.结果:监测信号稳定、清晰易辨,根据记录到的信号可进行不同清醒-睡眠状态分期,并判断大鼠的呼吸暂停情况.结论:该法操作简便,是小动物睡眠和呼吸监测的可靠方法.
|
| 关 键 词： | 睡眠 呼吸 监测 大鼠 |
| 文章编号： | 1000-6834(2004)03-0310-03 |
| 修稿时间： | 2003年12月22 |
The method of monitoring sleep state and respiratory rhythm in freely moving rats |
| |
| Wang J,Wang GF,Ling YL.The method of monitoring sleep state and respiratory rhythm in freely moving rats[J].Chinese Journal of Applied Physiology,2004,20(3):310-312. |
| |
| Authors: | Wang Jing Wang Guang-fa Ling Yi-ling |
| |
| Institution: | WANG Jing~1,WANG Guang-fa~ |
| |
| Abstract: | Aim: To devise a new method for testing the animal model of sleep apnea syndrome (SAS). Methods: We simultaneously monitoring the respiratory wave through a micro-pressure transducer and the electrical signals of both electrocorticogram (ECoG) and electromyogram (EMG), for detecting the sleep-wake states and the respiratory rhythm in rats. The recording data are analyzed by the manual-computer work. Results: The ECoG and EMG signals are stable and easily to distinguish. We can accurately detect the sleep-wake state and the sleep apnea events in rats by these signals. Conclusion: The method is reliable to test the small animal model of SAS, and is easily to operate. |
| |
| Keywords: | sleep respiration monitoring method rats |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ |
