A comprehensive perspective of traditional Arabic or Islamic medicinal plants as an adjuvant therapy against COVID-19 |
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| Institution: | 1. Department of Plant Biotechnology, Atta-Ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), 44000, Islamabad, Pakistan;2. The Standard College for Girls, 3/530 Paris Road, Sialkot Pakistan;3. School of Interdisciplinary Engineering & Sciences (SINES), National University of Sciences and Technology (NUST), 44000 Islamabad, Pakistan;4. Department of Biosciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan;5. Yunnan Herbal Laboratory, College of Ecology and Environmental Sciences, Yunnan University, Kunming 650091, China;6. Center for Applied Physics and Radiation Technologies, School of Engineering and Technology, Sunway University, Bandar Sunway 47500, Selangor, Malaysia;7. Caribbean Medical University, Willemastad, Curacao-Caribbean Island, Curaçao;8. Department of Chemistry, College of Science, King Khalid University, Abha 62529, Saudi Arabia;9. Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha 62529, Saudi Arabia;10. Department of Pharmacy, BGC Trust University Bangladesh, Chittagong 4381, Bangladesh;11. Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, Bangladesh |
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| Abstract: | COVID-19 is a pulmonary disease caused by SARS-CoV-2. More than 200 million individuals are infected by this globally. Pyrexia, coughing, shortness of breath, headaches, diarrhoea, sore throats, and body aches are among the typical symptoms of COVID-19. The virus enters into the host body by interacting with the ACE2 receptor. Despite many SARS-CoV-2 vaccines manufactured by distinct strategies but any evidence-based particular medication to combat COVID-19 is not available yet. However, further research is required to determine the safety and effectiveness profile of the present therapeutic approaches. In this study, we provide a summary of Traditional Arabic or Islamic medicinal (TAIM) plants' historical use and their present role as adjuvant therapy for COVID-19. Herein, six medicinal plants Aloe barbadensis Miller, Olea europaea, Trigonella foenum-graecum, Nigella sativa, Cassia angustifolia, and Ficus carica have been studied based upon their pharmacological activities against viral infections. These plants include phytochemicals that have antiviral, immunomodulatory, antiasthmatic, antipyretic, and antitussive properties. These bioactive substances could be employed to control symptoms and enhance the development of a possible COVID-19 medicinal synthesis. To determine whether or if these TAIMs may be used as adjuvant therapy and are appropriate, a detailed evaluation is advised. |
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| Keywords: | Traditional Arabic or Islamic medicinal plants COVID-19 Phytochemicals ACE2 Antiviral Adjuvant therapy SARS-CoV-2 Aleo vera |
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