A phytochemical in the edible Tamogi-take mushroom (Pleurotus cornucopiae), D-mannitol, inhibits ACE activity and lowers the blood pressure of spontaneously hypertensive rats |
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| Authors: | Hagiwara Shin-Ya Takahashi Masayuki Shen Yanbo Kaihou Shinobu Tomiyama Takahiro Yazawa Michio Tamai Yutaka Sin Yoosu Kazusaka Akio Terazawa Minoru |
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| Institution: | Three B Co., Inc., Nanporo, Japan. |
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| Abstract: | D-Mannitol, one of the main phytochemicals of the edible Tamogi-take mushroom (Pleurotus cornucopiae), was found to inhibit an angiotensin I converting enzyme (ACE). The antihypertensive effect of D-mannitol and a hot water extract of Tamogi-take mushroom was demonstrated in spontaneously hypertensive rats (SHR) by oral administration. |
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