Synthesis and cytotoxic evaluation of novel thiazolocarbazoles |
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| Authors: | Lamazzi Christelle Chabane Hadjila Thiery Valerie Pierre Alain Leonce Stephane Pfeiffer Bruno Renard Pierre Guillaumet Gérald Besson Thierry |
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| Institution: | Institut de Chimie Organique et Analytique, UMR-CNRS 6005, Université d'Orléans, rue de Chartres, BP 6759, F-45067 Orleans cedex 2, France. |
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| Abstract: | Novel thiazolocarbazole derivatives 4 and 5 have been synthesized via the corresponding imino-1,2,3-dithiazoles 3. In vitro antitumor activity of these polyheterocyclic compounds was studied and the results show that 2-cyano derivatives exhibit a medium in vitro antiproliferative effect. |
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