Cytokinesis: a logical GAP |
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| Authors: | Mishima Masanori Glotzer Michael |
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| Institution: | Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030, Vienna, Austria. |
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| Abstract: | Two complexes localize to the central spindle and regulate completion of cytokinesis: one, centralspindlin, contains a kinesin-like protein and a Rho-family GAP; the second contains Aurora B kinase. Aurora B kinase is known to regulate localization of centralspindlin and may regulate the activity of the RhoGAP component of centralspindlin. |
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