Identification of inorganic crystal-specific sequences using phage display combinatorial library of short peptides: A feasibility study |
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Authors: | Duncan JH Gaskin Karine Starck Evgeny N Vulfson |
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Institution: | (1) Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK |
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Abstract: | The feasibility of using a combinatorial phage display library of decapeptides to identify ligands which can interact with the surface of a crystal was assessed using geological calcium carbonate as a model. Two relatively strong binding clones were identified by ELISA, sequenced and the encoded oligopeptides were prepared by solid phase synthesis and their properties compared with those of casein hydrolysate. |
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Keywords: | combinatorial library crystal peptide phage display recognition |
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