Early evolution of cellular electron transport: Molecular models for the ferredoxin-rubredoxin-flavodoxin region |
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Authors: | Gunnar von Heijne Clas Blomberg Herrick Baltscheffsky |
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Affiliation: | (1) Research Group for Theoretical Biophysics, Dept. of Theoretical Physics, Royal Institute of Technology, S-100 44 Stockholm, Sweden;(2) Dept. of Biochemistry, Arrhenius Laboratory, University of Stockholm, S-106 91 Stockholm, Sweden |
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Abstract: | Using information from conformation-predicting algorithms and X-ray data, a possible mode of structural evolution from an ancestral molecule of about 28 residues to bacterial ferredoxins and rubredoxins is suggested. The possibility of a further evolutionary pathway leading to flavodoxinlike proteins is also indicated. |
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