Radiomodifying influence of camphor on sister-chromatid exchange induction in mouse bone marrow |
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Authors: | H C Goel S Singh S P Singh |
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Affiliation: | Institute of Nuclear Medicine and Allied Sciences, Delhi, India. |
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Abstract: | The frequency of sister-chromatid exchanges (SCE) in mouse bone marrow exposed to gamma-irradiation was used to assess the radiomodifying effect of camphor. Hoechst 33258 plus Giemsa was used for SCE analysis. The radiation-induced SCE frequency was significantly low after a single dose of camphor (0.5 microM/g b.w.) administered 30, 45 or 60 min before irradiation; the effect was enhanced with increasing time intervals. |
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