不同运动干预方式对糖尿病前期人群血糖相关指标影响的Meta分析

目的：系统评价有氧运动、抗阻运动、有氧联合抗阻运动三种不同干预方式对糖尿病前期人群血糖的影响。方法：制定文献检索策略，检索PubMed、EMBASE、EBSCO外文数据库以及CNKI、Wanfang中文数据库，以手工查阅检出文献和相关参考文献作为补充，查找符合纳入标准的随机对照试验进行质量评价，运用RevMan5.2统计软件对纳入的数据进行Meta分析，运动干预组和对照组间指标采用均数差（MD）评价。结果：共纳入原始文献8篇，与对照组相比，不同运动干预方式的综合效应对空腹血糖指标无显著性影响，与按不同干预方式进行亚组分析结果一致；有氧运动及有氧联合抗阻运动对餐后2h血糖指标有显著性降低的作用（P < 0.05）；有氧运动对胰岛素抵抗指数有显著降低作用。结论：对糖尿病前期人群，运动干预对餐后2 h血糖、胰岛素抵抗指数的影响与运动方式有关，但对空腹血糖的作用尚不能确定。

Meta-analysis on influence of different exercise intervention modes to blood glucose related indexes of pre-diabetes

Objective: To assess the influence of the different exercise intervention mode, aerobic exercise training(AET), resistance training(RT) and AET RT, on blood glucose of pre-diabetes. Methods: Literatures were identified from the PubMed, EMBASE, EBSCO, CNKI and Wanfang databases. Relevant journals or conference proceedings were also searched manually. The qualities of randomized con-trolled trials that conformed to inclusion criteria were evaluated. Meta-analysis of the obtained related data was completed utilizing RevMan 5.2 statistical software. Mean difference of index related in exercise intervention groups and control group were calculated across the studies. Results: Eight original literatures enrolled in this study. Compared with control group, combined effect of different exercise interventions on fast-ing blood glucose showed no significant, consistent with different intervention subgroups analysis. RT group and AET + RT group showed a sig-nificantly reduced role on 2 h postprandial blood index (P < 0.05). AET group showed a significantly reduced role on insulin resistance in-dex. Conclusion: To pre-diabetic, effects of exercise on postprandial 2 h blood glucose and insulin resistance index are related to modes of ex-ercise. Effects of exercise on fasting blood glucose, but still could not be determined.