|
|||||
|
|
Cytotoxic T cells and mycobacteria |
|
| Authors: | Silva C L Bonato V L Lima K M Coelho-Castelo A A Faccioli L H Sartori A De Souza A O Leão S C |
| Institution: | Department of Biochemistry and Immunology, School of Medicine of Ribeir?o Preto, University of S?o Paulo, Brazil. clsilva@fmrp.usp.br |
| Abstract: | How the immune system kills Mycobacterium tuberculosis is still a puzzle. The classical picture of killing due to phagocytosis by activated macrophages may be only partly correct. Based on recent evidence, we express here the view that cytotoxic T lymphocytes also make an important contribution and suggest that DNA vaccines might be a good way to enhance this. |
| Keywords: | Cytotoxic T lymphocyte Macrophage activation Cellular immune response DNA vaccine Gene therapy Mycobacterium tuberculosis |
| 本文献已被 PubMed 等数据库收录！ | |